Endocrine Abstracts

Introduction: The awareness of osteoporosis is essantial of treatment. We investigated the awareness of osteoporosis in the patients with postmenopausal women in the region of Northeastern Anatolia.Methods: Four hundred and two patients with postmenopausal women was included in this study. We detected the age of menopause, the conscience of osteoporosis in the postmenopousal period, DEXA reports, habits of regular walking, drinking of milk, and used to v...

Type 2 diabetes mellitus (T2DM) has historically been considered an exclusive disease of adulthood until late 1970’s when reports of increased prevalence in pediatric age group emerged in the literature. The concerning increase in the rate of diagnosis of T2DM in children and adolescents has continued parallel to the increasing rates of obesity. The disease is not specific to the United States, it has been recognized as a global problem.T2DM of yout...

Backgraound: The liver occupies a central position in lipid metabolism. Free fatty acids (FFAs) are taken up by the liver to join the hepatic pool of FFA, a portion of which the liver synthesizes. Fatty liver occurs when lipid accumulation exceeds the normal 5% of liver weight. In the macrovesicular type, large fat droplets balloon the liver cell, displacing the nucleus to the periphery of the cell, like an adipocyte. Triglyceride accumulates most commonly because it has the h...

Backgraound: Fatty liver can relate with arteriosclerosis. We investigated the atherogenic index in the patients with fatty liver.Methods: Ninety-one patients with hyperlipidemia and 47 healthy subjects were included in the study. Fasting plasma levels of lipids were detected. Liver echogenity was measured by 3.75 mHz ultrasound probe and was graded by comparison with renal paranchymal echogenity. Atherogenic index was calculated as the ratio of plasma l...

Background: Primary hyperparathyroidism (pHPT) is an important endocrinologic cause of metabolic bone disorder in human. The regulatory mechanism of the cells of parathyroid gland proliferation is not exactly known. Peroxisome proliferator-activated receptor-γ (PPARγ) is a member of nuclear receptor superfamily. PPARγ is expressed in adipose tissue at a high level. It plays a role on number of disorders such as adipose tissue differantiation, insulin sensivity, ...

Introduction: Berardinelli Seip Congenital Lypodystrophy (BSCL) is a rare otosomal recessive disease characterized by major criteria which are lypoatrophy, acromegaloid features, hepatomegaly, hypertriglyceridemia, insulin resistance and minor citeria which are hypertrophic cardiomyopathy, psycomotor retardation, hirsutism, precocious puberty, long bone cysts, phlebomegaly. The presence of three major criteria or two major plus two minor criteria required for diagnosis of BSCL...

Introduction: Papillary thyroid carcinoma (PTC) patients with distant metastasis (DM) have variable clinical forms. PTC mostly metastasizes to the regional cervical lymph node. Metastasis rate is approximately 20–90% available when diagnosed. In addition, the overall incidence of DM is approximately 10%. DM are usually to the lungs, bone and brain. Furthermore rarely liver, pancreas, skeletal muscle, adrenal gland, ovaries, sphenoid sinuses and submandibular gland metasta...

Introduction: Primary hyperparathyroidism (PHP) in pregnancy is very rare condition and the true incidence of PHP in pregnancy is not well known. PHP is associated with significant maternal and foetal morbidity and mortality. PHP is diagnosed based upon levels of blood calcium and parathyroid hormone (PTH) in normal renal function status. However diagnosis of PTH can be difficult, the physiological changes of pregnancy in calcium homeostasis such as maternal blood volume expan...

Introduction: Papillary thyroid carcinoma (PTC) is the most frequently occurring subtype of thyroid differentiated cancers. PTC frequently metastasizes to the cervical lymph node region and metastasis rate of approximately 20–90% is available when diagnosed. Distant metastasis are usually the lungs, bone and brain metastases. Furthermore rarely the adrenal gland, skeletal muscle, ovaries, submandibular gland, sphenoid sinuses, liver and pancreatic metastases can be occurr...

Objective: There is not sufficient data about oxidative stress in euthyroid Hashimoto (EH) and subclinical hypothyroid Hashimoto (SHH) disease. We studied oxidative stress with more oxidative stress tests in EH and SHH patients and assessed whether there is an association betweeen Hashimoto disease and PON1 phenotype.Materials and method: 35 EH and SHH patients and 38 control was included to the study. Comprehensive biochemistry, routine blood analysis, ...